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(A) Effect of doubling dilutions of HER TKIs and (B) other TKIs and cytotoxic agents on growth of human ovarian cancer cells. Tumour cells were grown in growth medium (2% FBS) with inhibitors or medium alone until control cells (only medium) were confluent. The proliferation of cancer cells was calculated as percentage of control cell growth, as described in Materials and methods. Each point is a representation of the mean ± SD.
