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. 2016 Sep 5;49(5):1825–1838. doi: 10.3892/ijo.2016.3678

Figure 2.

Figure 2

(A) Effect of various forms of HER TKIs on the basal level of phosphorylated HER family members and downstream cell signaling molecules in SKOV3 cells analysed on LI-COR Odyssey Scanner as described in Materials and methods. (B) Effect of afatinib, erlotinib, NVP-AEW541 crizotinib, paclitaxel, doxorubicin and cisplatin on the basal level and HRG-induced phosphorylation of HER family, IGF-1R, Met, and downstream cell signaling molecules, and on the expression level of CD44, in SKOV3 cells.