Table 3. Pathway analysis of differentially expressed genes encoded outside the HIVAN1 locus.
| Gene Set Name | # Genes in Overlap | p-value | FDRq-value | ||
|---|---|---|---|---|---|
| MARSON BOUND BY FOXP3 UNSTIMULATED | 26 | 1.78E-11 | 8.39E-08 | ||
| MIKKELSEN MEF HCP WITH H3K27ME3 | 17 | 7.30E-10 | 1.73E-06 | ||
| GRAESSMANN APOPTOSIS BY DOXORUBICINDN | 28 | 2.34E-09 | 2.76E-06 | ||
| HAMAIA POPTOSIS VIA TRAIL UP | 13 | 1.43E-06 | 8.44E-04 | ||
| MEISSNER NPCHCP WITH H3K4ME2 AND H3K27ME3 | 10 | 2.68E-06 | 1.27E-03 | ||
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP | 11 | 2.60E-05 | 6.81E-03 | ||
| DORN ADENOVIRUS INFECTION 24HR DN | 4 | 3.34E-05 | 7.25E-03 | ||
| PILON KLF1T ARGETS DN | 22 | 3.43E-05 | 7.25E-03 | ||
| NABA MATRISOME | 15 | 3.53E-05 | 7.25E-03 | ||
| BENPORATHES WITH H3K27ME3 | 15 | 9.01E-05 | 1.25E-02 | ||
| MIKKELSEN NPC HCP WITH H3K27ME3 | 8 | 1.10E-04 | 1.46E-02 | ||
| MIKKELSEN ES ICP WITH H3K4ME3 | 11 | 2.62E-04 | 2.57E-02 | ||
| PIDAVB3 INTEGRIN PATHWAY | 4 | 2.96E-04 | 2.64E-02 | ||
| DORN ADENOVIRUS INFECTION 12HR DN | 3 | 3.68E-04 | 3.08E-02 | ||
| NABA MATRISOME ASSOCIATED | 11 | 3.91E-04 | 3.08E-02 | ||
| DORNA DENOVIRUS INFECTION 32HR DN | 3 | 6.05E-04 | 4.09E-02 | ||
| DORN ADENOVIRUS INFECTION4 8HR DN | 3 | 6.52E-04 | 4.22E-02 | ||
| MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 | 13 | 6.69E-04 | 4.27E-02 | ||
Gene set names are from the Molecular signature database. Selected enriched pathways with FDR q-value <0.05 are shown. The full results of the pathway analyses are shown in Tables A and B in S2 Table.