Table 1.
Demographics and clinical findings in patients with nevi, indeterminate choroidal melanocytic lesions, choroidal melanomas, and other choroidal tumors, together with statistical comparison
| All tumors n=49 | Nevi n=19 | IMLs n=10 | Melanomas n=10 | Other choroidal tumors n=10 | |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 19 (38%) | 8 (42%) | 6 (60%) | 2 (20%) | 3 (30%) |
| Female | 30 (62%) | 11 (58%) | 4 (40%) | 8 (80%) | 7 (70%) |
| P-value | 0.450 | 0.414 | 0.694 | ||
| Age (years) | |||||
| Mean ± SD | 64±15 | 68±9 | 65±10 | 69±15 | 51±22 |
| Median (min–max) | 68 (18–93) | 69 (52–90) | 64 (53–85) | 70 (44–93) | 55 (18–74) |
| P-value | 0.377 | 0.701 | 0.094 | ||
| Affected eye | |||||
| OD | 24 (49%) | 11 (58%) | 5 (50%) | 5 (50%) | 3 (30%) |
| OS | 25 (51%) | 8 (42%) | 5 (50%) | 5 (50%) | 7 (70%) |
| P-value | 0.714 | 0.714 | 0.245 | ||
| Visual acuity (logMAR) | |||||
| Mean ± SD | 0.26±0.40 | 0.10±0.11 | 0.31±0.26 | 0.49±0.62 | 0.30±0.40 |
| Median (min–max) | 0.16 (0.0–2.0) | 0.10 (0.0–0.40) | 0.18 (0.0–0.7) | 0.30 (0.0–2.0) | 0.15 (0.0–1.22) |
| P-value | 0.016* | 0.040* | 0.308 | ||
| Tumor location distance to optic nerve (mm) | |||||
| Mean ± SD | 2.6±2.4 | 2.7±2.6 | 3.1±2.5 | 2.8±2.2 | 1.9±2.5 |
| Median (min–max) | 2.1 (0.0–9.3) | 2.2 (0.0–9.3) | 3.2 (0.0–7.5) | 2.6 (0.0–6.7) | 1.1 (0.0–7.8) |
| P-value | 0.573 | 0.804 | 0.286 | ||
| Distance to foveola (mm) | |||||
| Mean ± SD | 1.7±2.1 | 2.0±2.1 | 1.6±2.8 | 1.5±1.9 | 1.6±2.4 |
| Median (min–max) | 0.8 (0.0–7.5) | 1.3 (0.0–6.0) | 0.6 (0.0–7.5) | 0.5 (0.0–5.4) | 0.0 (0.0–6.0) |
| P-value | 0.429 | 0.429 | 0.429 | ||
| Tumor thickness (mm) | |||||
| Mean ± SD | 2.3±1.7 | 1.3±1.2 | 2.6±0.5 | 3.6±2.6 | 2.6±1.4 |
| Median (min–max) | 2.4 (0.0–11.0) | 1.8 (0.0–3.2) | 2.4 (1.9–3.3) | 3.1 (1.9–11.0) | 2.7 (1.0–4.6) |
| P-value | 0.005* | <0.001* | 0.027* | ||
| Largest basal diameter of tumor (mm) | |||||
| Mean ± SD | 6.4±3.2 | 4.1±1.6 | 7.5±3.3 | 8.6±3.1 | 7.4±3.3 |
| Median (min–max) | 6.0 (1.6–14.5) | 3.8 (2.1–8.5) | 8.3 (1.6–11.4) | 8.6 (3.7–13.3) | 7.0 (3.1–14.5) |
| P-value | 0.008* | <0.001* | 0.003* | ||
| Follow-up (months) | |||||
| Mean ± SD | 13.5±5.4 | 14.8±4.7 | 16.9±4.8 | 10.4±5.5 | 10.7±4.8 |
| Median (min–max) | 14.0 (5–23) | 15.0 (6–23) | 17.5 (7–22) | 7.5 (6–20) | 10.5 (5–19) |
| P-value | 0.247 | 0.045* | 0.040* | ||
Notes: P-value – nevus vs IML, melanoma, and other choroidal tumors.
*
denotes statistical significance.
Abbreviations: IML, indeterminate choroidal melanocytic lesion; logMAR, logarithm of the minimum angle of resolution; OD, right eye; OS, left eye; SD, standard deviation.