. Author manuscript; available in PMC: 2016 Nov 23.
Published in final edited form as: Nature. 2016 May 23;534(7605):115–118. doi: 10.1038/nature17955
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
Reprints and permissions information are available at www.nature.com/reprints.