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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Genet Epidemiol. 2016 Jun 17;40(6):461–469. doi: 10.1002/gepi.21983

Table II.

Simulation results for empirical TPRs for causal RV detection across simulation replications at a fixed FPR of 0.01. For comparisons across methods, the difference in TPR (Δ) and corresponding bootstrap 95% confidence interval are reported.

True Positive Rate

Method RR ν =5 ν =10 ν =15
P-BRI 1.5 0.324 0.288 0.265
L-BRI 0.253 0.262 0.250
 Δ (95% CI) 0.070 (0.056,0.086) 0.026 (0.012,0.038) 0.015 (0.002,0.027)

P-BRI 2.5 0.660 0.603 0.523
L-BRI 0.638 0.612 0.560
  Δ (95% CI) 0.022 (0.014,0.034) -0.009 (-0.020,0.001) -0.037 (-0.049,-0.022)

P-BRI 5.0 0.966 0.919 0.845
L-BRI 0.968 0.929 0.877
  Δ (95% CI) -0.002 (-0.006,0.001) -0.010 (-0.015,-0.007) -0.032 (-0.039,-0.024)