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Physiochemical characteristics of optimized 5-FU-NLC gel (mean ± SD, n=3)
| Serial number | Carbopol® 940 (%) | Drug content (%) | pH | Spreadability (cm) |
|---|---|---|---|---|
| 1 | 1.0 | 99.29±2.21 | 5.81±0.15 | 6.52±0.31 |
| 2 | 1.5 | 98.21±2.42 | 6.12±0.12 | 8.12±0.25 |
| 3 | 2.0 | 97.97±1.64 | 5.72±0.14 | 10.26±0.34 |
Abbreviations: Carbopol® 940, poly(acrylic acid); 5-FU, 5-fluorouracil; NLC, nanostructured lipid carrier; SD, standard deviation.
