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. 2016 Oct 5;9:167–174. doi: 10.2147/JIR.S119021

Figure 4.

Figure 4

adiponectin treatment and SIRT1 mRNA expression.

Notes: There was a significant increase in the expression of SIRT1 mRNA in FFA-fed macrophages vs BSA-fed macrophages. Moreover, adiponectin treatment showed decreased SIRT1 mRNA expression in BSA-fed macrophages compared to FFA-fed macrophages; there was a significant increase in SIRT1 mRNA expression with adiponectin treatment. *P<0.05 vs BSA + LPS; P<0.05 vs BSA + LPS + ADN; #P<0.05 vs FFA + LPS.

Abbreviations: BSA, bovine serum albumin; FFA, free fatty acid; LPS, lipopolysaccharide; SIRT1, sirtuin-1; ADN, adiponectin.