Table 1.
Body weight (g) Mean ± SEM |
MAP (mmHg) Mean ± SEM |
|||
---|---|---|---|---|
CTRL | DIO | CTRL | DIO | |
Sham | 26.75±0.36 | 36.83±1.07† | 61±2.24 | 65±4.46 |
Sepsis | 26.6±0.3 | 36.12±0.4† | 53.8±1.3* | 46.8±1.2*† |
Sepsis + adiponectin | 27.5±0.2 | 38.7±2.7† | 64.2±4.6# | 60.7±0.5# |
Notes: Body weight of CTRl and DIO sham, sepsis, and sepsis + adiponectin groups shows no significant differences from each other within the groups, and body weights of DIO mice were significantly higher than their CTRl counterparts. The MAPs in sepsis groups were significantly lower than their respective sham counterparts. The MAPs in sepsis + adiponectin groups were significantly higher compared to sepsis alone in both CTRl and DIO mice. Finally, MAP in DIO-sepsis groups was significantly lower compared to CTRl-sepsis groups.
P<0.05 vs respective sham;
P<0.05 vs respective sepsis;
P<0.05 vs respective CTRl.
Abbreviations: DIO, diet-induced obesity; CTRl, control; SEM, standard error of the mean.