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. 2016 Sep 22;7(4):649–663. doi: 10.1016/j.stemcr.2016.08.015

Figure 6.

Figure 6

Long-Term Motor Function Analyses after Transplantation of GSI-Pretreated hiPSC-NS/PCs

(A) Comparison of the BMS scores among the PBS, control, and GSI+ groups. Motor function in the hind limbs was assessed weekly for up to 89 days after transplantation using the BMS score (PBS group, n = 10; control group, n = 10; GSI+ group, n = 10 mice).

(B) Comparison of the rotarod test among the PBS, control, and GSI+ groups. The rotarod test was performed at 89 days after transplantation. Histograms show the total run time (PBS group, n = 10; control group, n = 10; GSI+ group, n = 10 mice).

(C) Comparison of the stride lengths among the PBS, control, and GSI+ groups. Treadmill gait analyses were performed at 89 days after transplantation using the DigiGait system. Histograms show the stride length (PBS group, n = 10; control group, n = 10; GSI+ group, n = 10 mice).

∗p < 0.05, ∗∗p < 0.01, and not significant (N.S.) according to two-way repeated-measures ANOVA with the Tukey-Kramer test (A) or one-way ANOVA with the Tukey-Kramer test (B and C). Data are presented as means ± SEM.