Table S3. Clinical outcomes among patients who underwent colorectal endoscopic submucosal dissection (analysis restricted to only studies published as full-text journal article).
| Outcomes | Studies, n | Tumor, n | Rate (95 % CI)1 |
| Efficacy measures | |||
| R0 resection | 41 | 6006 | 84 (80 – 87) |
| Endoscopic en bloc resection | 51 | 7862 | 93 (90 – 95) |
| Curative resection | 10 | 1614 | 87 (81 – 91) |
| Safety measures | |||
| Immediate perforation2 | 53 | 8184 | 4 (3 – 5) |
| Immediate major bleeding2 | 20 | 2154 | 0.82 (0.32 – 2.1) |
| Delayed perforation3 | 22 | 3313 | 0.24 (0.11 – 0.54) |
| Delayed bleeding3 | 47 | 7398 | 1.7 (1.2 – 2.4) |
| Recurrence (if R0)4 | 16 | 1999 | 0.05 (0.01 – 0.35) |
| Recurrence (if not R0)4 | 15 | 367 | 3.6 (1.3 – 9.9) |
| Recurrence (irrespective of R0 status)4 | 18 | 2391 | 0.58 (0.19 – 1.7) |
n, number; R0, histologically-confirmed en bloc resection
1
The rates are calculated as a percentage of the total number of tumors operated.
2
Immediate refers to adverse outcomes occurring within 24 hours of the procedure.
3
Delayed refers to adverse outcome occurring 24 hours after the procedure.
4
Average follow-up was ~18, 21 and 19 months for assessment of recurrence among tumors with R0, without R0, and irrespective of R0 status, respectively.