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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: J Comp Neurol. 2016 May 19;524(18):3696–3716. doi: 10.1002/cne.24025

Figure 5. P-cadherin appears diffusely distributed in albino RPE cells.

Figure 5

A: RPE flat mount at E15.5 and stained with anti-P-cadherin antibody. In pigmented RPE, P-cadherin outlines RPE cell membrane. In albino RPE, P-cadherin appears more diffuse (arrowheads) in both VT and the DT regions. B: Frontal sections of temporal retina at E15.5. P-cadherin labeling outlines RPE (red bracket) in pigmented retina in the VT and the DT regions. In albino RPE, P-cadherin labeling reveals a meshwork rather than an even outline of the cells. NR, neural retina. C, D: 3D reconstruction image of VT RPE flat mount at E15.5 stained with anti-P-cadherin antibody. C1, D1, volume image; C2, D2, slice image (Green, P-cadherin; blue, Hoechst staining). Z-plane images are presented at side. Image area width 34.92 µm, height 34.92 µm. Scale bars: 25 µm (A, B).