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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: J Comp Neurol. 2016 May 19;524(18):3696–3716. doi: 10.1002/cne.24025

Figure 6. Cx43 is expressed in between RPE cells and at the interface of RPE and neural retina in both albino and pigmented retina.

Figure 6

A–H: Frontal retinal sections collected at E15.5 bleached and stained with Zic2 (ipsilateral RGC marker, A) or Islet 1/2 (differentiated RGCs, E), Na+/K+ ATPase (RPE cell membranes, B, F) and Cx43 (gap junction, C, G). Red bracket regions in Zic2-positive RGC area of the VT region (A), or Islet 1/2-positive RGC area of the DT region (E) (shown in preceding reference sections) are magnified in panels B–D and F–H, Cx43 (C, G) and merged (D, H) micrographs in subsequent panels. Cx43 protein is detected as a punctate labeling in the RPE and at the interface between RPE and neural retina (arrowheads in C, G). Distribution of Cx43 particles is not different between genotypes. Scale bars: 15 µm (A, E), 10 µm (B, C, D, F, G, H).