Figure 3.
Low motor or cognition performance scores significantly correlate with high serum concentrations of 8,12-iso-iPF2α-VI isoprostane. Neuropsychological assessments were done using the Kaufman Assessment Battery for Children, 2nd edition (KABC-II) for cognition and the Bruininks/Oseretsky Test, 2nd Edition (BOT-2) measure for motor proficiency. (A) MPI (KABC-II) scores relative to serum concentration of 8,12-iso-iPF2α-VI isoprostane (triangles = konzo children, r = −0.78, P = 0.00; circles = non-konzo children, r = −0.24, P = 0.47). (B) BOT-2 scores relative to serum level of 8,12-iso-iPF2α-VI isoprostane (triangles = konzo children, r = −0.63, P < 0.01; circles = non-konzo children, r = −0.06, P = 0.86).51