Table 1.
Clinical and Demographic Data for 24 patients undergoing ATL/AH and Temporal Cortical RNA Expression Analysis
| Subject Number |
Seizure Frequency (/Month) |
Age (Years) |
Gender (M/F) |
Seizure Focus |
Duration (Years) |
Etiology | Outcome (SF/NSF) |
Follow- up (Months) |
|---|---|---|---|---|---|---|---|---|
| 1 | 60 | 19 | M | LMT* | 7 | TBI | NSF | 12 |
| 2 | 4 | 59 | F | RLT* | 11 | TBI | SF | 33 |
| 3 | 4 | 30 | M | RT# | 8 | Unk | SF | 34 |
| 4 | 10 | 46 | F | RT# | 5 | Unk | SF | 23 |
| 5 | 4 | 16 | M | RT# | 10 | Unk | SF | 12 |
| 6 | 6 | 12 | F | RMT* | 6 | Unk | SF | 23 |
| 7 | 2 | 58 | F | LT# | 22 | Unk | SF | 20 |
| 8 | 2 | 14 | F | RT# | 8 | TBI | NSF | 78 |
| 9 | 12 | 48 | F | LRT* | 35 | Unk | NSF | 23 |
| 10 | 8 | 31 | F | RT# | 16 | Unk | NSF | 33 |
| 11 | 10 | 38 | M | RT# | 37 | Feb | SF | 30 |
| 12 | 2 | 44 | F | LT# | 23 | TBI | NSF | 83 |
| 13 | 1 | 50 | F | LT# | 12 | Unk | SF | 42 |
| 14 | 4 | 32 | M | RT# | 29 | Unk | NSF | 5 |
| 15 | 1 | 29 | F | RT# | 23 | JD | SF | 72 |
| 16 | 4 | 32 | M | RT# | 17 | Unk | NSF | 94 |
| 17 | 20 | 41 | F | RT# | 21 | Unk | SF | 53 |
| 18 | 1 | 41 | M | RT# | 34 | Unk | SF | 53 |
| 19 | 105 | 24 | M | LT# | 23 | I | SF | 23 |
| 20 | 3 | 37 | M | LT# | 6 | CAV | SF | 37 |
| 21 | 2 | 36 | M | RT# | 18 | Unk | SF | 79 |
| 22 | 4 | 29 | F | LT# | 28 | ABI | SF | 83 |
| 23 | 4 | 48 | F | RLT* | 31 | Unk | SF | 47 |
| 24 | 30 | 38 | M | RT# | 33 | Unk | SF | 39 |
Subject No. = Subject number in the study; Seizure Freq = Pre-operative seizure frequency (average number of seizures/month); Age (yrs.) = Age in years at time of anterior temporal lobectomy with amygdalohippocampectomy (ATL/AH); M/F = Male/Female; Duration = pre-operative duration of epilepsy diagnosis; Seizure Focus = Seizure Focus (L = left, R = right, MT = medial temporal, LT = lateral temporal, RT = regional temporal lobe; RT= right temporal lobe, LT = left temporal lobe) localized by * = ictal subdural EEG recording or # = ictal scalp-EEG recording; Etiology = etiology of epilepsy, TBI = traumatic brain injury, Feb = febrile illness, JD = juvenile diabetes, I = DPT immunization, CAV = cavernous malformation, Unk = unknown; ANI = anoxic brain injury (botulism), Outcome = Post-operative ATL/AH seizure outcome (SF = seizure-free, NSF = not seizure-free); Follow-up (mos.) = post-operative follow-up after ATL/AH in months at which time seizure outcome was determined.