Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Flow diagram showing mechanisms by which arsenicals induce inflammation and tissue injury. This diagram also includes our recent findings defining the role of unfolded protein response (UPR) signaling in this intricate mechanism of molecular pathogenesis of tissue injury caused by exposure to arsenicals. *These agents show some efficacy against arsenic-induced tissue damage. **This indicates the effects of arsenic trioxide on macrophages.
