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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Hypertension. 2016 Sep 19;68(5):1171–1178. doi: 10.1161/HYPERTENSIONAHA.116.07666

Fig. 3. Ablation of the RyR2 Ser-2808 phosphorylation site prevents a CCH-dependent increase in fractional release (FR).

Fig. 3

(A,B) Representative line-scan images (top) and time-dependent profiles (bottom) for Ca transients and SR Ca content at low (60%) SR Ca loads under control conditions and in the presence of 10 μmol/L CCH. (C) Summary data for FR in S2808A cells at normal and low SR Ca contents (±SEM, n=6–11). SR Ca content was obtained by application of 20 mmol/L caffeine.