Table 1.
Clinical characteristics of inflammatory bowel disease patients with or without sleep disturbances
| Sleep disturbances (−) | Sleep disturbances (+) | p value | |
|---|---|---|---|
| (N = 76) | (N = 60) | ||
| Age (years) | 43.8 ± 15.3 | 41.5 ± 20.6 | 0.48 |
| Male sex (%) | 54.3 | 56.7 | 0.61 |
| Body mass index (kg/m2) | 21.6 ± 2.7 | 21.2 ± 3.6 | 0.57 |
| Alcohol drinking (%) | 26.3 | 31.7 | 0.57 |
| Smoking (%) | 6.6 | 16.7 | 0.10 |
| Caffeine intake (%) | 53.9 | 41.7 | 0.17 |
| IBD type | |||
| UC | 68.4 | 60.0 | 0.37 |
| CD | 31.6 | 40.0 | |
| Disease duration (years) | 11.7 ± 8.5 | 10.9 ± 8.8 | 0.57 |
| Active disease (%) | 14.5 | 18.3 | 0.64 |
| HBI | 1.08 ± 2.33 | 1.68 ± 2.90 | 0.42 |
| pMayo score | 1.19 ± 1.66 | 1.74 ± 1.96 | 0.18 |
| Prior IBD surgery (%) | 47.4 | 53.3 | 0.61 |
| Medication used | |||
| Steroids (%) | 2.6 | 5.0 | 0.65 |
| 5-aminosalicylates (%) | 78.9 | 78.3 | 1.00 |
| Immunomodulators (%) | 28.9 | 13.3 | 0.04 |
| Anti-TNF biologics (%) | 27.6 | 23.3 | 0.69 |
| Sleep medications (%) | 2.6 | 25.0 | <0.01 |
Data are expressed as mean ± SD, or frequency. IBD inflammatory bowel disease, UC ulcerative colitis, CD Crohn’s disease, HBI Harvey-Bradshaw Index, pMayo partial Mayo score, TNF tumor necrosis factor