Figure 8.

Adrenal expression of GH in rats. GH mRNA from an adrenal removed (control) and from the contralateral adrenal gland (24 hours after unilateral adrenalectomy) was retrotranscripted with specific primers, and the resultant cDNAs were resolved in 2% agarose and stained with ethidium bromide. GH products were detected in the expected molecular weight: 328 bp. Adrenalectomy markedly increased the expression of GH in the contralateral gland 24 hours after the adrenalectomy (Ax 24 h). This may indicate that, apart from ACTH action, GH is overexpressed in the adrenal gland for mediating the compensatory hypertrophy. Reprinted with permission of the publisher. Source: J Devesa, Devesa P, Reimunde P. Growth hormone: actions and preventive and therapeutic applications. Med Clin (Barc) 2010; 135 (14): 665-670. Copyright © 2009 Elsevier Spain, S.L. All rights reserved.

Abbreviation: MWM, molecular weight markers.