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KCl‐ and NA‐induced vasoconstriction in mouse SMAs
| Young WT (n = 5) | Adult WT (n = 5) | Young KO (n = 5) | Adult KO (n = 5) | |
|---|---|---|---|---|
| Delta tone (%) | (8–17 weeks) | (28–56 weeks) | (8–17 weeks) | (28–56 weeks) |
| KCl (75 mm) | 74.6 ± 3.7 | 87.5 ± 4.4 | 70.0 ± 4.5 | 87.4 ± 4.8 |
| KCl + NiCl2 (30 μm) | 61.9 ± 3.6 | 64.6 ± 13.8 | 59.6 ± 6.1 | 81.2 ± 5.5 |
| NA (1 μm) | 22.8 ± 4.0 | 47.0 ± 6.6* | 30.1 ± 5.7 | 49.5 ± 5.9 |
* P < 0.05 vs. young WT.
