Figure 8. In vivo impact of HKA2‐mediated Na⁺ secretion in the CCD .

Daily Na⁺ intake (A) and urinary Na⁺ excretion (B) in WT (white bars) and HKA2‐null mice (black bars) under normal conditions (control) and 1 day after switching to a high salt diet (3% NaCl in drinking water). Results are shown as the mean ± SEM (n = 5). ^* P < 0.05.