Table 2.
Adrenal steroidogenic gene expression levels
Unstressed | Stressed | 2‐way ANOVA | |||||
---|---|---|---|---|---|---|---|
Control | Restricted | Control | Restricted | Group | Stress | Interaction | |
Cyp21a1 | 1.08 ± 0.17 | 1.23 ± 0.18 | 1.42 ± 0.18 | 1.03 ± 0.08 | NS | NS | NS |
Cyp11b1 | 1.00 ± 0.04 | 1.10 ± 0.08 | 1.14 ± 0.07 | 1.18 ± 0.05 | NS | NS | NS |
Cyp11b2 | 1.01 ± 0.06 | 1.06 ± 0.09 | 1.15 ± 0.1 | 1.13 ± 0.12 | NS | NS | NS |
Hsd11b2 | 1.03 ± 0.10 | 1.10 ± 0.10 | 1.08 ± 0.10 | 1.22 ± 0.13 | NS | NS | NS |
Agtr1b | 1.06 ± 0.15 | 1.20 ± 0.15 | 1.52 ± 0.19 | 1.30 ± 0.14 | NS | NS | NS |
Pnmt | 1.21 ± 0.26 | 1.43 ± 0.27 | 1.44 ± 0.25 | 0.97 ± 0.13 | NS | NS | NS |
Igf1r | 1.01 ± 0.06 | 1.02 ± 0.05 | 1.07 ± 0.07 | 1.14 ± 0.09 | NS | NS | NS |
Th | 1.04 ± 0.11 | 1.19 ± 0.14 | 1.27 ± 0.16 | 1.31 ± 0.04 | NS | NS | NS |
Effects of growth restriction and maternal stress on adrenal mRNA expression of steroidogenenic genes (mean ± SEM; n = 7–8 per group). NS, not significant.