Figure 2. Changes in respiratory and cardiovascular variables during control and PECO trials in COPD patients and healthy participants .

Change in $\dot{V}$, MAP and HR from baseline, and $P_{\mathrm{ETC}{\mathrm{O}}_2}$ during each minute of the control trial and PECO trial in COPD patients and healthy participants. The black bar indicates the period of circulatory occlusion. ^*Significant difference from Baseline value (P < 0.05). ^†Significant difference between COPD patients and healthy participants.