Figure 2.

Metabolic Benefits of RYGB Are Driven by a Humoral Factor

(A and B) Insulin (A) and glucagon (B) secretion from rat islets treated for 48 hr with serum from sham- (black) or RYGB-operated (gray bars) animals. Data are presented as percentage of basal secretion (mean ± SEM as percentage of content; insulin: sham, 0.974 ± 0.064; RYGB, 2.274 ± 0.0749; glucagon: sham, 0.748 ± 0.032; RYGB, 5.251 ± 0.947; n = 8 rats, five or six experiments). ^∗p < 0.05, ^∗∗p < 0.01 versus 1 mM glucose sham, ^††p < 0.01 versus 1mM glucose RYGB, ^#p < 0.05 for indicated comparisons.

See also Figure S3.