Figure 4. Noise reduction elucidated in diploid background and the model predictions.

(a) Single-cell expression histograms showing the response of the natural (wild type) GAL network in diploid cells (WP128, bars) at different galactose concentrations along with the model prediction (red). (b) Single-cell expression histograms showing the response of the synthetic network in diploid cells (WP196, bars) at different galactose concentrations along with the model prediction (orange). (c) Coefficient of variation for the expression level of ON cells in diploid cells carrying wild type (blue) or synthetic (green) networks at the given galactose concentrations. Error bars indicate s.e.m. (N=4).