FIGURE 9.

Distribution of open and closed conformations in GspDAH7PS with or without prephenate in solution. Theoretical scattering profiles were generated from models of both the prephenate-free open form (blue line) and the prephenate-bound closed form (red line) using OLIGOMER. These theoretical profiles were compared with the experimental GspDAH7PS SAXS data (open circles) in both the absence (A) and the presence (B) of prephenate. The experimental SAXS data were fitted to a distribution of both open and closed forms using OLIGOMER (yellow dashed line), and column charts show the percentages of open and closed forms GspDAH7PS adopted in solution with and without prephenate.