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. 2016 Aug 22;291(42):21848–21856. doi: 10.1074/jbc.C116.732990

FIGURE 1.

FIGURE 1.

Parameters after 8 weeks of diet reversal, i.e. from the 17th week to the 24th week of the study. A, growth curve with body weights taken every week. B–F, glucose (B), triglycerides (C), cholesterol (D), blood urea nitrogen (E), and creatinine (F) measured at the end of the study after diet reversal. CONTROL, rats fed with normal pellet diet; HFD, rats fed with high fat diet; REV, reversal group rats fed with normal pellet diet for 8 weeks following 16 weeks of high fat diet feeding; REV+MET, reversal group rats fed with normal pellet diet and treated with metformin (100 mg kg−1 day−1, p.o.) after 16 weeks of high fat diet feeding. *, p < 0.05, **, p < 0.01, ***, p < 0.001 versus CONTROL; #, p < 0.05, ##, p < 0.01, ###, p < 0.001 versus HFD; @, p < 0.05, @@@, p < 0.001 versus REV; n = 6.