Skeletal muscle GRK2 deletion does not impair exercise capacity.
A–D, treadmill exercise performance. After an acclimatization period, mice were run on a treadmill with increasing speed until exhaustion was reached (engaging the shock grid for 5 s). The mean time to exhaustion (A), maximum speed reached (B), distance covered (C), and frequency per minute of shock grid engagement (D) were calculated from individual performances. Bars depict mean values, and error bars represent S.D., n = 6- 9 mice per group.