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. 2016 Oct 14;22(38):8497–8508. doi: 10.3748/wjg.v22.i38.8497

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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Effect of dietary ethanol and/or guanidinoacetate ingestion on serum homocysteine, insulin, non-essential fatty acid and hepatic non-essential fatty acid levels. Rats were fed the Lieber DeCarli control or ethanol diet with or without 0.36% GAA supplementation. After 6 wk of feeding, serum homocysteine (A) insulin (B) NEFA (C) and hepatic NEFA (Dlevels were determined by HPLC or biochemical analysis as detailed in the Materials and Methods section. The data shown are means ± SEM of 5 determinations. Values not sharing a common subscript letter are statistically different, P < 0.05 vs control. GAA: Guanidinoacetate; NEFA: Non-essential fatty acid.