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. 2016 Oct 12;4(19):e12993. doi: 10.14814/phy2.12993

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© 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Perivascular adipose tissue (PVAT) adipocyte phenotype varies depending on sex and anatomical location in 10‐week‐old Sprague–Dawley rats. (A) Distribution of white adipocyte areas in aortic (aPVAT) and mesenteric (mPVAT) PVAT, and perigonadal fat (GON), n = 6. Representative low and high‐magnification images of aPVAT, mPVAT, and GON stained with hematoxylin and eosin (B) and with antibodies against UCP1 (C) from male and female rats. Scale bars = 0.22 mm (low magnification) and 110 μm (high magnification). Arrows indicate adipocytes exhibiting UCP1 staining in mPVAT.