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. 2016 Oct 14;7:171. doi: 10.3389/fpsyt.2016.00171

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Copyright © 2016 Pittaras, Faure, Leray, Moraitopoulou, Cressant, Rabat, Meunier, Fossier and Granon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the MGT experimental design [Adapted from Ref. (8)]. White circle represented food pellets and black circle quinine pellets. “Advantageous” choices gave access to one food pellets and then to 3 or 4 food pellets (18/20) or quinine pellets (2/20). “Disadvantageous” choices gave access to 4 or 5 food pellets (1/20) or quinine pellets (19/20). We distinguished “advantageous” choices from “disadvantageous” ones because mice earned more pellets (74 or 92 pellets vs. 45 or 44 pellets) after 20 trials by choosing the “advantageous” ones.