Table 1. Summaries of six patients with perianal or vulva EMPD.

Clinicopathological factor	Patient number
	1	2	3	4	5	6
Clinical findings
Tumor location	Perianal	Perianal	Vulva	Perianal	Vulva	Vulva
Sex	Male	Female	Female	Male	Male	Male
Age at diagnosis (yr)	74	69	81	78	75	74
Chief complaint	Eczema	Eczema	Eczema and itching	Eczema	Eczema	Eczema and itching
Duration of symptom (mo)	72	36	30	2	84	120
Mapping biopsy of the anal canal
Number of biopsies	12	12	21	Not performed	16	12
Biopsy-positive site	DL	0.5-cm above DL	Anal verge	-	Anal verge	Anal verge
Surgical findings
Surgical procedure	WLE	WLE	WLE	WLE+APR	WLE	WLE
Reconstruction method	STSG	STSG	STSG	STSG	STSG	STSG
Lymph node dissection	No	No	Yes	No	Yes	No
Covering colostomy	Yes	Yes	No	-	No	No
Pathological findings
Resection margin	Negative	Negative	Negative	Positive	Negative	Negative
Histological stage	Intraepithelial	Intraepithelial	Invasive	Intraepithelial	Invasive	Intraepithelial
Lymph node metastasis	No	No	Yes	No	Yes	No
Outcomes
Graft infection	Yes	No	Yes	No	Yes	No
Postoperative hospital stay (d)	86	51	72	24	82	22
Tumor recurrence	No	No	Yes	No	Yes	No
Prognosis	Alive	Alive	Died	Alive	Alive	Alive
Disease free survival (mo)	37.2	112	2.9	50.2	13.1	5.8
Overall survival (mo)	37.2	112	12.8	50.2	37.4	5.8

EMPD: extramammary Paget disease, DL: dentate line, WLE: wide local excision, APR: abdominoperineal resection, STSG: split thickness skin graft.