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. 2016 Oct 13;36(21):2715–2727. doi: 10.1128/MCB.00138-16

FIG 7.

FIG 7

Overexpression of CD36 affected arachidonic acid metabolism and decreased hepatic levels of prostaglandins and 20-HETE. All the mice were fed an HFD for 19 weeks, and the CD36Tg mice were treated or not treated with Dox. (A) Hepatic prostaglandin levels. (B) Hepatic arachidonic acid levels. (C) Hepatic expression of Cox-1 and Cox-2. (D) Hepatic 20-HETE level. (E) Hepatic expression of 20-HETE-producing Cyp4a/Cyp4f enzymes. n = 6 for all groups. *, P < 0.05; **, P < 0.01; n.s., not statistically significant. The data are presented as means and SEM.