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. 2016;29(Suppl 1):120–123. doi: 10.1590/0102-6720201600S10029

TABLE 1. Methodological characteristics of the selected studies, type of interventions and results.

Reference (year) Type of study Study location Period of follow-up N * Tipe of surgery ** age Sex*** Type of medication Type of administration Individual Doses Time of medical therapy Conclusion
Vasconcelos RS et. al 2010 25 Case Series Brazil From 7 to 22 months n=29 RYGB >18 years F Calcium e Vitamin D (tablets and diet) people 600mg Diet +200mg tablet of Ca and 500 IU Vitamin D (per day) From 7 to 22 months There were no significant differences between the average bone mass density and prevalence of vertebral fractures in both groups.
Flores L. et. al 2010 10 Prospective cohort study Espain 1 year n=222 RYGBL 18-65 Years F e M Calcium and Vitamin D (tablets) people 1,200 mg Ca and 800 IU Vitamin D (per day) 4,8 e 12 months The parathyroid hormone leads cortical bone destruction and improving serum Ca. 80% of patients have vitamin D deficiency but not bone fractures.
Williams SE. et al 2008 27 Case study United States 2 years N=1 RYGB 56 years F Cálcium vitamin D (tablets) person 500mg Ca and 400 IU (per day) 2 years After 2 years the patient showed no fracture or risk to bone fracture level.
Avgerinos DV. et al 2007 2 A prospective cohort study United States 2 years N=444 (M=91 F=353) RYGB 21-64 years M e F Cálciume vitamin D (tablets) people 1,200 mg Ca and 800IU VitaminaD 1.8 years Total calcium decreases in body related mobilization of bone. Supplementation with vitamin D prevent the decrease in bone calcium.
Riedt CS et. al 2006 19 A prospective cohort study Unites States 6 months N=21 RYGB and RYGBL (5:open field and 16 laparoscopy) 29-62 years F Cálcium Vitamin D (tablets, diet and injected) people Diet, 1,000 mg of Ca and 400 IU Vitamin D 6 months Low Ca absorption after surgery, being considered markers of bone resorption (60 to 200%). There was a higher bone resorption than bone formation