Table 3.

Univariate analyses in 41 patients with primary hepatic lymphoma.

Variable	No.	5-year OS, %	95% CI	10-year OS,%	95% CI	P value*
All patients	41	77	64-90	59	42-76
Age
>62	21	70	50-90	49	25-73	0.07
<62	20	84	68-100	69	46-92
Gender
Male	27	77	61-93	60	39-81	0.90
Female	14	79	57-100	57	27-87
Surgery
Yes	4	100	-	100	-	0.12
No	37	75	61-89	56	38-74
Hemoglobin level
Normal	30	86	73-99	65	45-85	0.13
Lower than normal	11	55	26-85	44	14-74
Liver function tests
Normal	18	78	59-97	69	46-92	0.86
Elevated	23	77	59-95	52	29-75
Radiological presentation
Solitary	15	71	47-95	71	47-95	0.52
Multiple or diffuse	26	80	64-96	54	32-76
Pre-existing liver disease
Yes	13	76	52-99	63	33-93	0.86
No	28	78	62-94	58	38-79
Splenomegaly
Yes	4	38	0-94	38	0-94	0.37
No	37	81	68-94	61	43-79
Hepatomegaly
Yes	7	71	38-100	54	15-93	0.78
No	34	78	64-92	60	41-79
Night sweats
Yes	4	100	-	75	33-100	0.24
No	37	75	61-89	57	39-75
Weight loss
Yes	7	57	20-94	57	20-94	0.14
No	34	81	68-94	59	40-78
Fever
Yes	8	100	-	86	60-100	0.03
No	33	72	56-88	53	33-73
B-symptoms (night sweats, weight loss, fever)
Yes	13	77	54-99	68	42-94	0.67
No	28	78	62-94	54	32-76
Nausea/vomiting
Yes	7	86	60-100	57	20-94	0.55
No	34	75	60-90	61	42-80
Anorexia
Yes	6	67	29-100	67	29-100	0.80
No	35	79	65-93	57	38-76
Jaundice
Yes	6	83	53-100	83	53-100	0.88
No	35	76	62-90	54	35-73
Fatigue
Yes	9	78	51-100	47	10-84	0.19
No	32	77	62-92	63	44-82
Abdominal pain or discomfort
Yes	22	72	53-91	49	26-72	0.25
No	19	83	66-100	74	51-97
Treatment modality
Chemotherapy alone	26	77	61-93	61	40-82	0.59
Other	15	79	58-100	56	26-86
Histopathology
Diffuse large B-cell	27	81	66-96	65	45-85	0.69
Others	14	71	47-95	45	12-78

*Log rank test. OS, overall survival; CI, confidence interval.