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. 2016 Aug 2;6(10):e00538. doi: 10.1002/brb3.538

Table 1.

Baseline characteristics

Characteristic All GMG OMG Remission p‐value
n (%) 200 119 39 42
Age, year, mean (SD) 58 (17) 56 (17) 60 (15) 61 (17) .235
Age at disease onset, mean (SD) 48 (20) 45 (21) 53 (17) 52 (20) .032
Female sex, n (%) 107 (53.5) 76 (63.9) 12 (30.8) 19 (45.2) .001
Disease duration, year, median (IQR) 6 (2–15) 7 (3–16) 3 (2–10) 6 (2–10) .014
Antibody status, n (%) (1 missing)
AchR 166 (83.4) 98 (83.1) 30 (76.9) 38 (90.5) .258
MuSK 6 (3.0) 5 (4.2) 1 (2.6) .535
Negative 27 (13.6) 15 (12.7) 8 (20.5) 4 (9.5) .322
Medication, n (%)
Cholinesterase inhibitors 173 (86.5) 107 (89.9) 37 (94.9) 29 (69.0) .001
Glucocorticoids 111 (55.5) 68 (57.1) 23 (59.0) 20 (47.6) .502
Immunosuppressants 116 (58.0) 81 (68.1) 10 (25.6) 25 (59.5) <.001
None 4 (2.0) 1 (0.8) 3 (7.1) .064
Thymectomy, n (%) (9 missings) 99 (51.8) 68 (59.6) 9 (24.3) 22 (55.0) .001
Thymoma 24 (24.2) 18 (75.0) 3 (12.5) 3 (12.5) .380
Thymus hyperplasia 31 (31.3) 21 (67.7) 2 (6.5) 8 (25.8) .736
Comedication, n (%)
Antidepressants 18 (9.0) 15 (12.6) 2 (5.1) 1 (2.4) .089
NSAIDs 13 (6.5) 8 (6.7) 2 (5.1) 3 (7.1) .924
Opioids 8 (4.0) 7 (5.9) 1 (2.6) 0 (0.0) .217

GMG, generalized myasthenia gravis; OMG, ocular myasthenia gravis; AchR, acetylcholine receptor; MuSK, muscle‐specific tyrosine kinase.

p‐values refer to overall group comparisons of patients with generalized MG, ocular MG, and pharmacological remission.