Table 2.
Prevalence and severity of relevant fatigue, prevalence of mood, anxiety, and sleep disorders
| Parameter | All | GMG | OMG | Remission | p‐value |
|---|---|---|---|---|---|
| n | 196 | 116 | 39 | 41 | |
| CFQ ≥ 4 items, n (%) | 110 (56.1) | 83 (71.6) | 14 (35.9) | 13 (31.7) | <.001 |
| CFQ‐T score, mean (SD) | 15.6 (6.2) | 17.5 (6.0) | 14.0 (5.6) | 11.7 (5.0) | <.001 |
| CFQ‐P score, mean (SD) | 10.7 (4.5) | 12.1 (4.3) | 9.4 (4.1) | 7.8 (3.7) | <.001 |
| CFQ‐M score, mean (SD) | 4.9 (2.3) | 5.4 (2.4) | 4.7 (2.2) | 3.9 (1.9) | .002 |
| CF ≥ 6 months within n = 108 patients with relevant fatigue, n (%) (2 missings) | 76 (70.4) | 59 (72.0) | 9 (64.3) | 8 (66.7) | .808 |
| HADS‐D ≥ 8 points, n (%) (6 missings) | 38 (19.6) | 28 (24.6) | 6 (15.4) | 4 (9.8) | .093 |
| HADS‐A ≥ 8 points, n (%) (6 missings) | 54 (27.8) | 41 (36.0) | 7 (17.9) | 6 (14.6) | .010 |
| ISI ≥ 10 points, n (%) | 83 (41.5) | 61 (51.3) | 12 (30.8) | 10 (23,8) | .003 |
GMG, generalized myasthenia gravis; OMG, ocular myasthenia gravis; CFQ, Chalder Fatigue Scale; CFQ‐T, CFQ‐Total; CFQ‐P, CFQ‐Physical; CFQ‐M, CFQ‐Mental; CF, chronic fatigue (≥6 months); ISI, Insomnia Severity Index; HADS, Hospital Anxiety and Depression Scale; HADS‐D, HADS‐Depression; HADS‐A, HADS‐Anxiety; MG‐ADL, MG activities of daily living profile.
p‐values refer to overall group comparisons of patients with generalized MG, ocular MG, and pharmacological remission.