Table 2. Variable Parameters Associated With Advanced Fibrosis (F3 + F4) According to Univariate and Multivariate Analyses.

	Advanced Fibrosis (F3 + F4)
	UVA			MVA
	OR	95% CI	P-value	OR	95% CI	P-value
Age	1.040	1.006–1.075	0.0206	1.018	0.969–1.070	0.4700
BMI	1.014	0.910–1.131	0.7981
Platelet	0.936	0.878–0.999	0.0476	0.981	0.888–1.084	0.7059
Albumin	0.456	0.166–1.257	0.1292
AST	1.014	1.002–1.026	0.0216	1.007	0.993–1.022	0.3273
ALT	1.000	0.995–1.005	0.9678
YKL-40	1.010	1.004–1.017	0.0013	1.007	1.000–1.014	0.0412
Type IV collagen 7s	2.505	1.613–3.889	<0.0001	1.974	1.316–2.962	0.0010
Hyaluronic acid	1.017	1.004–1.030	0.0092	0.997	0.991–1.003	0.3496
WFA+-M2BP	2.516	1.312–4.828	0.0055	1.190	0.604–2.345	0.6146
APRI	3.460	1.720–6.959	0.0005
FIB-4-index	1.937	1.388–0.066	0.0001

UVA, univariate analysis; MVA, multivariate analysis; OR, odds ratio; CI, confidence interval.

BMI, APRI, see Table 1.