. 2016 Oct 14;6:35112. doi: 10.1038/srep35112

Table 2. Summary of secondary metabolites identified in extracts of P. arizonense and predicted biosynthetic gene clusters.

Detected compound	Most similar biosynthetic gene cluster	Orthologous genes^b	Avg. similarity [% ID/% coverage]
Austalide B, J^a, K, L, novel isomers C₂₅H₃₂O₈ and C₂₆H₃₄O₉	Cluster 4: Similarity to a mycophenolic acid cluster⁵⁸	3/8	59/96
6-Farnesyl-5-7-dihydroxy-4-methylphthalide^a	Cluster 4: Similarity to a mycophenolic acid cluster⁵⁸	3/8	59/96
Pyripyropene A^a, E, F, O	Cluster 5: Similarity to a pyripyropene cluster⁴⁵	7/9	79/99
Tryptoquivaline C^a or 27-epi-Tryptoquivaline^a, G or L, I, M or 27-epi-Nortryptoquivaline	Cluster 3: Similarity to a tryptoquialanine cluster⁶⁷	13/13	74/96
Fumagillin^a	Cluster 34: Similarity to an intertwined fumagillin/pseurotin cluster⁷¹,⁹⁵	16/16	82/95
Pseurotin A^a		16/16	82/95
Xanthoepocin	Cluster 2: Similarity to an aurofusarin cluster⁷⁹,⁸⁰	7/11	49/96
Curvulinic acid^a	n.d.	n.a.	n.a.
n.d.	Cluster 28: Similarity to an acetylaranotin cluster⁸³	9/9	68/91

All compounds were found in extract of P. arizonense IBT 12295, 12287 and 12289. ^aconfirmed with a standard.

^bNumber of genes in the predicted P. arizonense gene cluster which are orthologous (more than 30% identity and 50% coverage) to a gene in the reference gene cluster. For detailed information about the detected gene clusters see Supplementary Data S1 and S2.