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. 2016 Oct 14;6:34962. doi: 10.1038/srep34962

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Copyright © 2016, The Author(s)

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Depletion of either the master transcription factor ERa or the pioneer transcription factor FOXA1 in MCF7 cells decreases MED1 and SMC1 recruitment at regulatory elements of the TFF1 and GREB1 genes in MCF7. Amplified enhancer (E1 and E2) and TSS regions are indicated by boxes. Enrichment fold were calculated relative to control regions without MED1 or SMC1 signal. The bar graphs display the enrichment fold of a representative experiment. Error bars show the standard error of the mean for technical qPCR triplicates.