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. 2016 Jul-Sep;9(3):165–171. doi: 10.4103/0974-2077.191650

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Copyright: © Journal of Cutaneous and Aesthetic Surgery

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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(a) A transverse scalp biopsy from apparently healthy individual showed negative cytokeratin 19 immunostaining in the inner layers (red arrow), outer layers (black arrow) of hair follicle, and epidermis (blue arrow) (IHC, ×200). (b) A transverse scalp biopsy of nonscarring alopecia stained with CK19 showed one large differentiated hair follicle which was negative in the outer layers (black arrow) and inner layers (red arrow) of hair follicle and another small primitive hair follicle that showed positivity with marked intensity in the inner layers (yellow arrow) of hair follicle while the outer layers (green arrow) were negative (IHC, ×200). (c) A transverse scalp biopsy of scarring alopecia showed distorted hair follicle and positive cytokeratin 19 immunostaining with mild intensity in the outer layers (black arrow) of distorted hair follicle while the inner layers (red arrow) were negative (IHC, ×400)