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. 2015 Dec 31;56(7):835–844. doi: 10.1002/jcph.668

Figure 3.

Figure 3

Observed 3‐ to 6‐month treatment scaling factor is independent of various covariates tested. Scaling factor λ was not statistically significantly impacted by the various covariates tested, including (a) drug class, (b) baseline DAS28 score, (c) the magnitude of control arm ACR50 at 3 months, and (d) averaged patient disease duration. Dotted line shows the model‐predicted scaling factor (λ = 0.997). Symbol size in scatter plots reflects the sample size in each treatment arm.