Table 2.

Data Sets Used in Different Analysis Scenarios^*

Data Set	Analysis Scenarios	Number of Trials	Number of Arms	Number of Patients	Number of Drug Classes	Number of Drugs
1	ACR50 exploratory assessment	68	257	27 176	13	28
2	3‐ to 6‐ month ACR50	40	117	17 330	7	12
3	3‐ to 12‐ month ACR50	11	27	5606	5	7
4	2‐ to 6‐ month ACR50	32	87	15 152	6	11
5	DAS28 exploratory assessment	22	69	6560	6	10
6	1‐ to 6‐ month DAS28	12	29	4551	6	7
7	Additional data for extended analysis	4	9	901	2	2

*Data were included only if the trial had ACR50 or DAS28 reported at both time points of interest for each scenario.