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. 2016 Oct 13;14:290. doi: 10.1186/s12967-016-1044-0

Table 4.

Univariate tests of significance (ANCOVA)

Univariate tests of significance (ANCOVA)
Observations Dependent variables (pre–post Δ) Categorical predictors (ΔIF vs ΔND) Covariates (baseline values) P values
Body weight −0.40 ± 1.76 −0.97 ± 1.58 vs 0.16 ± 1.78 84.63 ± 6.17 0.0354
FM (kg) −0.96 ± 1.72 −1.61 ± 1.53 vs −0.30 ± 1.70 11.12 ± 3.98 0.0070
Adiponectin (μg/mL) −0.45 ± 3.07 2.04 ± 1.52 vs −2.94 ± 1.97 12.83 ± 1.98 0.0000
Leptin (ng/mL) 0.09 ± 0.67 −0.36 ± 0.31 vs 0.54 ± 0.64 1.97 ± 0.52 0.0000
IL-6 (ng/L) −0.15 ± 0.27 −0.25 ± 0.30 vs −0.04 ± 0.20 1.28 ± 0.31 0.0378
TNF-α (ng/L) −0.14 ± 0.47 −0.45 ± 0.37 vs 0.17 ± 0.34 5.63 ± 0.83 0.0000
IL-1β (ng/L) −0.05 ± 0.14 −0.12 ± 0.15 vs 0.02 ± 0.09 0.92 ± 0.15 0.0000
Testosterone total (nmol/L) −2.07 ± 3.60 −4.40 ± 3.02 vs 0.25 ± 2.43 19.93 ± 6.00 0.0000
IGF-1 (ng/mL) −12.38 ± 33.04 −28.00 ± 40.11 vs 3.23 ± 11.13 216.32 ± 38.84 0.0003

The Δ pre–post for each depended variable group were considered and the baseline values of the outcomes were adopted as covariate; TRF vs ND were assumed as categorical predictors