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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2016 Sep 5;310:60–67. doi: 10.1016/j.taap.2016.08.021

Fig. 4.

Fig. 4

Ileal gene and protein expression in vehicle- or GW4064-treated pregnant mice. (A) mRNA and (B) protein expression of Fxr-regulated targets were quantified in ilea from vehicle- and GW4064-treated virgin and pregnant mice on gestation day 14. Western blot staining of Fgf15 protein was performed using whole ileal homogenates. Data were normalized to vehicle-treated virgin controls (set to 1.0) and presented as mean relative expression ± SE (n=5–6). Black bars represent vehicle-treated mice and grey diagonal striped bars represent GW4064-treated mice. Asterisks (*) represent statistically significant difference (p≤0.05) compared with vehicle-treated virgin mice. Double daggers (‡) represent statistically significant difference (p≤0.05) compared with vehicle-treated pregnant mice.