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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Semin Oncol. 2016 Jun 14;43(4):453–463. doi: 10.1053/j.seminoncol.2016.06.003

Figure 1. DNA damage multiplex assay utilized on an A375 melanoma xenograft sample 2 hours after beginning treatment with topotecan at 1.5 mg/kg.

Figure 1

False color assignments are as follows: Rad51 (pink), pS343-Nbs1 (green), ERCC1 (cyan), and γH2AX (red). A representative 60× image is shown. Cells expressing both pS343-Nbs1 (green) and γH2AX (red) are yellow on the merged image. Scale bar = 20 µm.