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. 2016 Aug 2;157(11):2605–2616. doi: 10.1097/j.pain.0000000000000681

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© 2016 International Association for the Study of Pain

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Figure 1. — The murine mammary adenocarcinoma cell line 66.1 expresses the cystine/glutamate antiporter system x_c⁻. (A) Representative images of 66.1 XCT and DAPI staining, as indicated. 66.1 cell glutamate release was quantified over a 24-hour period in untreated cells (B), and at 18 hours in those exposed to vehicle, sulfasalazine (SSZ) (C) or (S)-4-carboxyphenylglycine (CPG-4) (D). Asterisks denote values statistically different from time 0 or vehicle control group, *P < 0.05, **P < 0.01, ***P < 0.001.