Fig 3. Vimar modulates the mitochondrial length in the high calcium condition.

(A) Effect of the Drp1 mutation on mitochondrial fission in high calcium conditions. a and b, Mitochondrial dendrites in the larval chordotonal neurons in the control flies (Appl>mitoGFP at 18°C and Appl>mitoGFP, tub-Gal80^ts at 30°C). c and d, Mitochondrial morphology in the AGM and AGM/drp1¹ flies. a'-d' are the enlarged view from the boxed area in a-d, and the mitochondrial lengths in a'-d' were quantified. 10 to 16 chordotonal organs from each genotype were examined. (B) Effect of the vimar overexpression on the mitochondrial length after induction of AGM expression for 26 hours. 10 to 16 chordotonal organs were examined for each genotype. (C) Effect of vimar mutant (vimar^k16722) on the mitochondrial fragmentation of the AGM flies. 10 to 16 chordotonal organs were examined for each genotype. (D) Effect of Miro overexpression and the vimar mutant on the mitochondrial fragmentation of the AGM flies. 10 to 16 chordotonal neurons were examined for each genotype.