Fig 1.

Pulsed-field gel electrophoresis (PFGE) analysis (A) and phylogenetic spa type analysis of (B) of ST8/SCCmecIVc MRSA strains isolated in Russia. The MRSA strains shown are those described in Table 1. In A, strains were classified into two major groups: IN, those with a megabase inversion, and non-IN, those without a megabase inversion. The geographical location of MRSA isolation is colored: yellow, European Russia (Moscow, St. Petersburg, and Yaroslavl); red, Siberian Russia (Krasnoyarsk); green, Far Eastern Russia (Vladivostok). Square, isolated from a fatal case; asterisk, isolated from a healthy carrier. tUK, tUnknown (unknown Ridom spa number). Lvx, levofloxacin; Rif, rifampicin. In B, spa allele numbers and Ridom spa repeat numbers (in parentheses) are both shown. spa1(t008) represents the ancestral spa type for Russian ST8/SCCmecIVc MRSA; other spa types diverged directly from the common ancestral type. Lvx^s, levofloxacin-susceptible; Rif^s, rifampicin-susceptible; Lvx^r, levofloxacin-resistant; Rif^r, rifampicin-resistant.