Table 1.
Characteristics of eligible studies included
| Author | Year | Controltype | Nationality | Ethnicity | Disease | Control | Case | P for HWE | Score | Genotyping method | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A-1082G | Total | AA | AG | GG | Total | AA | AG | GG | ||||||||
| Peddireddy et al31 | 2016 | HB | India | Asians | NSCLC | 250 | 130 | 84 | 36 | 246 | 156 | 69 | 21 | <0.05 | 7 | PCR-RFLP |
| Hsia et al32 | 2014 | HB | People’s Republic of China | Asians | Lung neoplasms | 716 | 561 | 130 | 25 | 358 | 273 | 69 | 16 | <0.05 | 7 | PCR-RFLP |
| Hart et al34 | 2011 | HB | Norway | Caucasians | NSCLC | 435 | 104 | 226 | 105 | 436 | 120 | 207 | 109 | 0.41 | 7 | TaqMan |
| Hao et al37 | 2009 | HB | People’s Republic of China | Asians | Lung neoplasms | 52 | 46 | 6 | 44 | 36 | 7 | 0.99 | 8 | TaqMan | ||
| Colakogullari et al30 | 2007 | HB | Turkey | Caucasians | Lung neoplasms | 59 | 33 | 21 | 5 | 44 | 11 | 30 | 3 | 0.53 | 7 | PCR-SSP |
| Shih et al28 | 2005 | HB | People’s Republic of China | Asians | NSCLC | 205 | 194 | 11 | 0 | 154 | 115 | 39 | 0 | 0.69 | 8 | PCR-RFLP |
| Seifart et al29 | 2005 | HB | Germany | Caucasians | Lung neoplasms | 243 | 86 | 115 | 42 | 39 | 6 | 21 | 12 | 0.74 | 7 | PCR-RFLP |
| A-592C | Total | CC | CA | AA | Total | CC | CA | AA | ||||||||
| Zhang et al33 | 2015 | HB | People’s Republic of China | Asians | Lung neoplasms | 336 | 75 | 176 | 85 | 330 | 110 | 156 | 64 | 0.37 | 7 | PCR-RFLP |
| Hsia et al32 | 2014 | HB | People’s Republic of China | Asians | Lung neoplasms | 716 | 71 | 277 | 368 | 358 | 40 | 145 | 173 | 0.08 | 7 | PCR-RFLP |
| Hart et al34 | 2011 | HB | Norway | Caucasians | NSCLC | 433 | 243 | 175 | 15 | 434 | 264 | 144 | 26 | <0.05 | 7 | TaqMan |
| Liang et al35 | 2011 | HB | People’s Republic of China | Asians | NSCLC | 120 | 7 | 44 | 69 | 116 | 11 | 36 | 69 | 0.99 | 8 | PCR-RFLP |
| Vogel et al36 | 2008 | PB | Denmark | Caucasians | NSCLC | 744 | 452 | 250 | 42 | 403 | 241 | 149 | 13 | 0.34 | 8 | PCR-RFLP |
| Colakogullari et al30 | 2007 | HB | Turkey | Caucasians | Lung neoplasms | 59 | 27 | 25 | 7 | 44 | 19 | 23 | 2 | 0.74 | 7 | PCR-SSP |
| Shih et al28 | 2005 | HB | People’s Republic of China | Asians | NSCLC | 205 | 13 | 76 | 116 | 154 | 18 | 70 | 66 | 0.91 | 8 | PCR-RFLP |
| T-819C | Total | TT | TC | CC | Total | TT | TC | CC | ||||||||
| Zhang et al33 | 2015 | HB | People’s Republic of China | Asians | Lung neoplasms | 336 | 145 | 144 | 47 | 330 | 108 | 135 | 87 | 0.25 | 7 | PCR-RFLP |
| Hsia et al32 | 2014 | HB | People’s Republic of China | Asians | Lung neoplasms | 716 | 372 | 265 | 79 | 358 | 212 | 128 | 18 | <0.05 | 7 | PCR-RFLP |
| Colakogullari et al30 | 2007 | HB | Turkey | Caucasians | Lung neoplasms | 59 | 7 | 26 | 26 | 44 | 2 | 23 | 19 | 0.9 | 7 | PCR-SSP |
| Shih et al28 | 2005 | HB | People’s Republic of China | Asians | NSCLC | 205 | 104 | 86 | 15 | 154 | 66 | 58 | 30 | 0.63 | 8 | PCR-RFLP |
| Seifart et al29 | 2005 | HB | Germany | Caucasians | Lung neoplasms | 242 | 14 | 88 | 140 | 40 | 2 | 14 | 24 | 0.97 | 7 | PCR-RFLP |
Abbreviations: HB, control hospital based; PB, control population based; NSCLC, non-small-cell lung cancer; PCR, polymerase chain reaction; RFLP, restricted fragment length polymorphism; SSP, sequence specific primer.